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Latest:
Next Steps in Tackling CDKL5 Deficiency Disorder Following First Approval: Elia Pestana-Knight, MDThe pediatric epileptologist from Cleveland Clinic provided commentary on the changes needed to improve research and drug development in CDKL5 deficiency disorder, as well as the organizations committed to advancing the state of care. [WATCH TIME: 3 minutes]
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Applying the Innovation Biodesign Framework to Promote Equity and Green Activity in Dementia CareLassell et al present a use case demonstrating the process of moving an unmet need to the “solution space” of the Innovation Biodesign Framework for addressing a healthcare challenge in a specific at-risk population: Alzheimer disease and AD-related dementias.
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Targeting Neuroinflammation in Huntington Disease: Rajeev Kumar, MDThe medical director of the Rocky Mountain Movement Disorders Center talked about the motivations of the phase 2 study on ANX005 for Huntington disease at the 2023 AAN Annual Meeting. [WATCH TIME: 3 minutes]
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Expanding Neuropalliative Care to New Disease States: Benzi Kluger, MD, MSThe president of the International Neuropalliative Care Society detailed potential disease states that could benefit from neuropalliative care as well as the importance of the patient community in expanding this type of approach. [WATCH TIME: 4 minutes]
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Effectiveness and Promise of Glatiramer Acetate Depot in Progressive Multiple Sclerosis: Ehud MaromThe president and chief executive officer of Mapi Pharma discussed the positive phase 2 findings of a new formulation of glatiramer acetate to treat progressive forms of MS, as well as the long-term plans for the drug. [WATCH TIME: 5 minutes]
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Not Your Grandmother’s Dopamine: PMD Alliance Releases On-Demand CME Topics in Advanced Therapeutics in Movement-Related DisordersThe PMD Alliance has developed a group of 6 on-demand CME events and live panel discussions, in partnership with MedStar Georgetown University Hospital, taking place on October 23-24, 2021, developed and presented by Yasar Torres-Yaghi, MD , and Fernando Pagan, MD.
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Capabilities of Deep Brain Stimulation to Modulate Late-Stage Neuroplasticity: Kenneth Baker, PhDThe associate staff member in the department of neurology at Cleveland Clinic discussed the major take-home points and post-hoc findings from a positive study of deep brain stimulation in poststroke patients. [WATCH TIME: 3 minutes]
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FDA to Add Warning Related to Guillain-Barré Syndrome on Johnson & Johnson VaccineSince vaccine administration, the CDC has announced 100 preliminary cases of Guillain-Barré syndrome.
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A Team Approach to Asleep Deep Brain StimulationHenry Ford Health System’s investment in advanced DBS technology and its commitment to multidisciplinary care has helped them become a leading treatment center for Parkinson disease and related movement disorders.
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Assessing the Impact of Gut Microbiota on Neuroprotection in Alzheimer Disease: Yannick J. Wadop Ngouongo, PhDThe postdoctoral researcher at The University of Texas Health Science Center at San Antonio talked the gut microbiome and neurological disorders, focusing on the potential role of gut microbiota imbalance in the pathogenesis of conditions like Alzheimer disease. [WATCH TIME: 5 minutes]
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AUPN Leadership Minute Episode 38: Visa Issues for FacultyEpisode 38 of the AUPN Leadership Minute features Muhammad "Mud" Alvi, MD, of West Virginia University Robert C. Byrd Health; and David B. Watson, MD, of West Virginia University Robert C. Byrd Health. [WATCH TIME: 5 minutes]
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Effects of Long-term CPAP Therapy in Multiple Sclerosis: Daria Trojan, MD, MScThe associate professor in the department of neurology and neurosurgery at McGill University discussed results from a study on the long-term use of continuous positive airway pressure treatment among patients with multiple sclerosis and sleep apnea presented at MSMilan 2023. [WATCH TIME: 5 minutes]
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Promising Disease-Modifying Therapies in Parkinson DiseaseDespite years of use of gold-standard therapy levodopa, therapeutic development in Parkinson disease has advanced rapidly and expanded to numerous novel pathways and targets.
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Key Considerations in Treatment of Spinal Muscular Atrophy / Considerações essenciais para o tratamento da atrofia muscular espinhalThe expert panel shares clinical pearls for treatment and management of Spinal Muscular Atrophy. O painel de especialistas compartilha recomendações valiosas para o tratamento e manejo da atrofia muscular espinhal.
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Aducanumab’s Implications for Future Clinical Trials: Pierre N. Tariot, MDIn addition to his work study pimavanserin in treating dementia-related psychosis, the director of the Banner Alzheimer’s Institute commented on the potential for aducanumab in Alzheimer disease.
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Challenges With Addressing Neurodegeneration in Poststroke Patients: Stephen FromThe chief executive officer of Aruna Bio discussed the reasons for the failure of neuroprotective agents in ischemic stroke trials and why AB126 has potential to restore neurodegeneration in such affected patients. [WATCH TIME: 3 minutes]
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Role of Cholinergic Transcripts in Sex-Specific Declines of Alzheimer Disease: Hermona Seroq, PhDThe professor of molecular neuroscience at the Edmond and Lily Safra Center for Brain Sciences discussed the premise behind a study of RNA-sequencing data to better understand the reasons why females suffer accelerated dementia. [WATCH TIME: 9 minutes]
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Trends in Movement Disorder Research: Ihtsham ul Haq, MD, FAANThe chief of Movement Disorders Division at the University of Miami Miller School of Medicine discussed some of the recent focused efforts to uncover more about Parkinson disease and what is on the horizon.
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Jonathan Graff-Radford, MD: Blood Tests as a Diagnostic Innovation in Alzheimer DiseaseThe neurologist at Mayo Clinic detailed promising diagnostic tools, including the revelation of blood tests in patients with Alzheimer disease.
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CNS Demyelination and Autoimmune Neurology: Spencer Hutto, MDThe fellow of autoimmune neurology at Massachusetts General Hospital also discussed concerns of associations between multiple sclerosis and COVID-19.
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Elias Kouchakji, MD: Investigating Pamrevlumab for DMD in Phase 3 LELANTOS StudyThe senior vice president of clinical development, drug safety, and pharmacovigilance at FibroGen provides details of the phase 3 LELANTOS trial of pamrevlumab in Duchenne muscular dystrophy.
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Weighing Approaches on Preventive Use, Medication Overuse in Chronic Migraine: Vincent Martin, MDThe president of the National Headache Foundation discussed whether switching or continuing preventive medications has a benefit in patients who have chronic migraine with medication overuse. [WATCH TIME: 4 minutes]
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Future Research Regarding Anticoagulant Use in Reducing Recurrent Stroke: Alexander Merkler, MD, MSThe assistant professor of neurology at Weill Cornell Medicine discussed his future aspirations to uncover more about the beneficial effects of anticoagulants in reducing recurrent stroke. [WATCH TIME: 3 minutes]
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Current Roadblocks Toward Expanding Gene Therapy Across Pediatric Neurology: Shafali Jeste, MDThe chief of neurology and co-director of the Neurological Institute at the Children’s Hospital Los Angeles described some of the major resource and policy-level barriers for gene therapy in pediatric neurological conditions. [WATCH TIME: 6 minutes]
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Shaping the Future of Medical Research Using Insights From the Headache Community: Amynah Pradhan, PhDThe associate professor of psychiatry at the University of Illinois at Chicago talked about the importance of diverse insight and perspectives from the headache community in shaping medical research priorities. [WATCH TIME: 3 minutes]
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AUPN 2022 Veterans Health Administration WorkshopGlenn Graham, MD, PhD; and Sharyl Martini, MD, PhD, moderate a discussion with 4 clincial experts to advance specialized clinical care, education and research for Veterans with movement disorders, multiple sclerosis, epilepsy and seizures, and headache. [WATCH TIME: 1 hour, 52 minutes]
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Key Takeaways From a Study of FUS in Early AD Dementia: Ali Rezai, MDThe executive chair at the Rockefeller Neuroscience Institute at West Virginia University shed light on early data from a small sample of patients with early Alzheimer disease who underwent focused ultrasound treatment. [WATCH TIME: 5 minutes]
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Anecdotal Evidence and the Need for Trials of Psychedelics in Headache Disorders: Bryan Roth, MD, PhDThe Michael Hooker Distinguished Professor and director of the NIMH psychoactive drug screening program at University of North Carolina School of Medicine discussed the need for large placebo-controlled trials of psychedelics in migraine disorders. [WATCH TIME: 4 minutes]
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Improving Patient Communication in MGExpert neurologists share thoughts on how to improve patient/physician communication and how listening to the patient needs will aid in managing MG.
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Next Steps for ATA188, Research Related to EBV and Multiple Sclerosis: AJ Joshi, MDThe chief medical officer at Atara Biotherapeutics provided insight on the future direction of its investigational agent ATA188 following new data that suggested a link between Epstein-Barr virus and multiple sclerosis. [WATCH TIME: 4 minutes]
