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Thomas P. Bravo, MD

PACAP: Lessons From A Potent Migraine Inducer?

May 11, 2015
  • Thomas P. Bravo, MD
  • Bert B. Vargas, MD

PACAP38 is a potent aggravator of migraine, a new study shows. This provides several new potential therapeutic targets -- most prominently a specific PACAP receptor PAC1.

  • READ >>
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An Imaging Biomarker for Migraine?

May 5, 2015
  • Thomas P. Bravo, MD
  • Bert B. Vargas, MD

Intriguing research is helping to shape our understanding of the functional connectivity and brain structure of migraineurs.

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©Suzanne Tucker/Shutterstock.com

New Insights on Post-Traumatic Headache

April 23, 2015
  • Thomas P. Bravo, MD
  • Bert B. Vargas, MD

Highlights of the first large study to describe the characteristics of post-traumatic headache and treatment response in children are summarized here.

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©Sebastian Kaulitzki/Shutterstock.com

A Novel Acute Migraine Treatment

April 23, 2015
  • Thomas P. Bravo, MD
  • Bert B. Vargas, MD

A novel drug-device may not only be a promising non-oral triptan acute migraine treatment, but may be more efficacious than its oral counterpart.

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Sphenopalatine Ganglion Block for Migraine?

April 7, 2015
  • Thomas P. Bravo, MD
  • Rashmi B. Halker, MD

The SPG is a promising target for migraine treatment, but robust evidence of efficacy for routine use of noninvasive device–mediated SPG blockade is needed.

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Poor Acute Treatment May Lead to Chronic Migraine

March 4, 2015
  • Thomas P. Bravo, MD
  • Todd J. Schwedt, MD

Efficacy of acute medication matters beyond just treating a single migraine. It may increase the risk of worsened disease.

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 hepatoxicity in humans

Migraine Preventative Butterbur Has Safety Concerns

January 28, 2015
  • Thomas P. Bravo, MD
  • Bert B. Vargas, MD

Despite butterbur’s potential efficacy, doubts are increasing about its long-term safety given of the risk of liver damage and the lack of an actively regulated preparation.

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sTMS: Promising Migraine Therapy

January 9, 2015
  • Thomas P. Bravo, MD
  • Amaal J. Starling, MD

Transcranial magnetic stimulation is a promising, effective, well-tolerated and safe treatment option for migraine with and without aura, episodic or chronic.

  • READ >>

Imploding or Exploding: Headache Direction May Help Select Treatment

October 17, 2014
  • Thomas P. Bravo, MD
  • Todd J. Schwedt, MD

Knowing the direction of the headache's origin, while clinically difficult to ascertain on a consistent basis, has shown some predictive value for migraines.

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Migraine Rx in the ED: A Systematic Review

September 2, 2014
  • Thomas P. Bravo, MD
  • David W. Dodick, MD

Here: highlights from a systematic review that these authors view as a substantial step forward in establishing an evidence-based approach to migraine treatment in the acute care setting.

  • READ >>

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