The phase 3 study will commence following the results of the phase 2b/3 AB10015 study, in which masitinib significantly slowed disease progression in combination with riluzole.
Amyotrophic Lateral Sclerosis
Your patient is a former linebacker with recently diagnosed amyotrophic lateral sclerosis, who asks if football injuries caused his disease. What will you tell him?
Scientists find that Schwann cells protect nerves against blood clotting factors that cause degeneration.
An emerging class of cancer drugs may help treat brain disorders such as amyotrophic lateral sclerosis frontotemporal dementia.
If your patient is a construction worker, bus driver, gas station attendant, or mechanic, take notice: “This type of exposure deserves more attention and study as we work to develop a better understanding of what causes ALS,” notes the author of a recent study.
A new study has found that an RNA-binding protein called TDP-43 could be a promising new biomarker for diagnosing amyotropic lateral sclerosis.
Although there is no cure for ALS, there are treatments available that can improve the quality of life and prolong survival.
What neuropsychiatric conditions are relatives of people with ALS at risk for? Are other genes involved besides C9orf72?
A genetic mutation suspected to be associated with amyotrophic lateral sclerosis risk has been confirmed through a large-scale research effort.
Serum testing for NMDAR and other autoantibodies is fraught with pitfalls, and careful clinical consideration is important.