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Migraine and Ischemic Stroke: Atherosclerosis Link?

Migraine and Ischemic Stroke: Atherosclerosis Link?


  • Although migraine is a risk factor for ischemic stroke, it is associated with other vascular diseases as well. Scroll through the slides for new insights on the associations between migraine and cerebrovascular atherosclerosis.

  • Van and colleagues[1] investigated the associations between migraine and cerebrovascular atherosclerosis. Here's what they found.


  • Data from the Dutch Acute Stroke Study was used to investigate associations between migraine and cerebrovascular atherosclerosis in 656 patients with acute ischemic stroke. Fifty-three patients had a history of migraine. Migraine was not associated with a difference in atherosclerotic changes in intracranial (adjusted risk ratio=0.82; 95% CI, 0.64-1.05) or extracranial (adjusted RR=0.93; 95% CI, 0.77-1.12) vessels.


  • Patients with and without migraine had similar internal carotid artery calcification volumes.

  • Migraine resulting in ischemic stroke may be related to biological mechanisms and not to macrovascular cerebral atherosclerosis.

  • 1. Van Os HJA, Mulder IA, Broersen A, et al. Migraine and cerebrovascular atherosclerosis in patients with ischemic stroke. Stoke. Epub 2017 May 19. https://www.ncbi.nlm.nih.gov/pubmed/28526767

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