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Neurology in the News: Migraine, Childhood Epilepsy, and More

Neurology in the News: Migraine, Childhood Epilepsy, and More

  • New studies shed light on topics such as nonencephalic pain and headache chronicity; benign childhood epilepsy with centrotemporal spikes and social cognition; and causal triggers of Alzheimer disease onset. Scroll through the slides for the stories and links to the studies.

  • Data from the CaMEO study indicate that noncephalic pain may be a marker for headache chronicity that might be used to predict risk for chronic migraine in people with episodic migraine and people with chronic migraine at risk for persistent chronic migraine.[1] See: Comorbid pain and migraine chronicity


  • Reduced bilateral fMRI activation in the insular cortex, caudate, and lentiform nuclei, and increased response time were seen in children with BCETS who were shown fearful faces. The findings suggest that BCECTS is associated with altered social cognition network and function.[2] See: Behavioral and fMRI responses to fearful faces are altered in benign childhood epilepsy with centrotemporal spikes (BCECTS)


  • Genome-wide variants associated with Alzheimer disease were identified that point to immunity and inflammation as causal triggers of disease onset.[3] See: Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.


  • Certification guidelines for accreditation training programs in neuroendovascular surgery and for subspecialty certification.[4] See: Training Standards in Neuroendovascular Surgery

  • References
    1. Scher AI, Buse DC, Fanning KM, et al. Comorbid Pain and Migraine Chronicity: The Chronic Migraine Epidemiology and Outcomes (CaMEO) Study. Neurology. 2017;89:461-468.
    2. Ciumas C, Laurent A, Saignavongs M, et al. Behaviroal and fMRI response to fearful faces are altered in benign childhood epilepsy with centrotemporal spikes (BCECTS). Epilepsia. July 31, 2017; Epub ahead of print.
    3. Sims R, van der Lee SJ, Naj AC, et al. Rare coding variants in PLCG2, AB13, and TREM2 implicate microglial-mediated innate immunity in Alzheimer disease. Nat Genet. July 17, 2017; Epub ahead of print.
    4. Day AL, Siddiqui AH, Meyers PM, et al. Training Standards in Neuroendovascular Surgery: Program Accreditation and Practitioner Certification. Stroke. 2017;48:2318-2315.

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