A cohort study of over 10,000 participants published in JAMA Neurology looked at the relationship between midlife risk factors and late-onset epilepsy.1
The findings . . . hypertension, diabetes, smoking, apolipoprotein E genotype, incident stroke and dementia were associated with and increased risk of late epilepsy starting at age 60. However, moderate alcohol intake and physical activity lowered the risk.
1. Johnson EL, Krauss GL, Lee AK, et al. Association Between Midlife Risk Factors and Late-Onset Epilepsy: Results From the Atherosclerosis Risk in Communities Study. JAMA Neurol. 2018 Jul 23. [Epub ahead of print].